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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

Using two separate drugs to shed weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err along the side of caution and allow FDA do its job and demand some investigation be done so your public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on the medications.

Researchers found that participants taking this drug to get a year, dropped a few pounds within 4 weeks and have kept the weight off during the entire 56 weeks of the study. Contrave is often a combination with the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them more efficient and safer.

Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular is the fact that by right now there aren't any long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure levels and heart rate, and shouldn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not be used in patients with uncontrolled high hypertension, and also by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

"This may be the first drug I'm conscious of that targets both the appetite and reward centres inside the brain," he said.